The Digimon Sovereigns live on the sixth, deepest plain of the Digital World, along with the Catalyst, or Shining Digivolution. They were some of the first Digimon to reach their highest form, and in an attempt to distance themselves from humans, they ironically took the appearance of the humans' gods.
When the D-Reaper begins to re-emerge, the four Sovereigns cannot agree on a strategy. Zhuqiaomon believes that they should use the Shining Digivolution to allow Digimon to digivolve and fight back, while Azulongmon believes that it is the Digimon's ability to grow in strength that brought the D-Reaper out in the first place. He has the DigiGnomes transform the Shining Digivolution into Calumon.
With the loss of the power to digivolve, Zhuqiaomon, thinking that the Digimon can instead grow stronger by defeating humanity, send his Deva into the Real World. Soon, his servant Makuramon discovers Calumon and attempts to return him to Zhuqiaomon, causing the Tamers to follow him in an attempt to rescue their friend. Makuramon, however, loses Calumon, and the Tamers find him, but Caturamon recaptures him.
After being separated, and a long, difficult trek across the Digital World, the Tamers arrive at Zhuqiaomon's domain. As they battle him, Azulongmon makes his appearance. Meanwhile, Ryo Akiyama encounters Ebonwumon and Baihumon in the latter's domain, and soon, they all gather in Zhuqiaomon's area, just as the D-Reaper begins to make its appearance.
Here, a compromise is made, and the Sovereigns implore Calumon to release his power so Digimon can digivolve and fight back. Thus, it is Zhuqiaomon's plan that prevails in the end, even though that does not excuse his methods in attacking the Tamers. The Sovereigns lead their new army of Mega Digimon to fight the D-Reaper in the Digital World. Later, they travel to the Real World and help the Tamers by dragging the Cable Reaper back into the Digital World during Operation: Doodlebug, removing it from the battle.
One of the Sovereigns is the final boss of Digimon Tamers: Digimon Medley, where a defeated Impmon is captured by him. The Tamers must defeat the Sovereign to rescue Impmon, and the Sovereign leaves with cryptic advice after the Tamers' victory.
Ryo Akiyama and Cyberdramon encounter Ebonwumon in Baihumon's territory, which he guards while Baihumon fights the D-Reaper, but then Baihumon returns, wounded. Later on, Baihumon and Ebonwumon meet with Azulongmon and Zhuqiaomon on how to handle the D-Reaper situation and helps Calumon release the Shining Digivolution, which digivolves every Digimon in the Digital World to their Mega forms to help the Sovereigns. In the final battle against the D-Reaper, Ebonwumon assists Azulongmon, Baihumon and Zhuqiaomon into dragging the Cable Reaper back into the Digital World during Operation: Doodlebug, thus saving the Tamers from having to defeat it all over again.
Zhuqiaomon sends his servants, the Deva, to find and capture Calumon. Makuramon captures him and attempts but fails to bring him to Zhuqiaomon. Zhuqiaomon is also behind Impmon's digivolution to Beelzemon. Caturamon later brings Calumon to Zhuqiaomon, and he places Calumon in a pit. When Antylamon becomes Suzie Wong's partner, Zhuqiaomon's power dedigivolves her into Lopmon. During the battle between Beelzemon and Gallantmon, he sends Caturamon to destroy Lopmon. Gallantmon destroys Caturamon, whose data Beelzemon absorbs.
When the Tamers finally confront Zhuqiaomon, he inflicts severe damage to Rapidmon before Henry Wong and Terriermon biomerge to MegaGargomon and defeat him. Zhuqiaomon, who the Tamers think is destroyed, emerges and then battles Gallantmon until the Eastern Guardian Azulongmon appears and stops the battle. During Azulongmon's story, Zhuqiaomon reveals the Catalyst where Calumon's power comes from. He takes the Tamers to Calumon's pit, but temporarily[please confirm] loses a wing during the rescue. Baihumon and Ebonwumon meet with them to talk about the D-Reaper problem, and Zhuqiaomon helps to release Calumon's Shining Digivolution power, digivolving every Digimon to its Mega Form. When the Tamers start to fight the D-Reaper in the Real World, Zhuqiaomon sends Dobermon with a gift: the ability to biomerge in the Real World. In the final battle against the D-Reaper, Zhuqiaomon assists Azulongmon, Baihumon, and Ebonwumon into dragging the Cable Reaper back into the Digital World during Operation: Doodlebug, thus saving the Tamers.
Azulongmon first appears when Zhuqiaomon attacks the Tamers. He saves the humans and their partner Digimon before fighting against Zhuqiaomon. He finally convinces Zhuqiaomon to not attack the Tamers so that they can focus on the true enemy, the D-Reaper. He tells the Tamers the history of the Digital World and each of its layers. He and Zhuqiaomon later meet with Baihumon and Ebonwumon to discuss the D-Reaper situation and helps to release Calumon's Shining Digivolution power, which digivolves every Digimon to their Mega forms. In the final battle against the D-Reaper, Azulongmon assists Zhuqiaomon, Ebonwumon, and Baihumon into dragging the D-Reaper back into the Digital World during Operation: Doodlebug, thus saving the Tamers.
Baihumon lives in the White Tower at the highest plain in the Digital World. When Ryo Akiyama and Cyberdramon arrive in his part of the domain, they find the Northern guardian Ebonwumon watching over his place as he fights the D-Reaper. Shortly after, Baihumon appears and collapses from exhaustion. Later on, Baihumon and Ebonwumon meet with Azulongmon and Zhuqiaomon on how to handle the D-Reaper situation and help Calumon release the Shining Digivolution which digivolves every Digimon in the Digital World to their Mega forms to help the Sovereigns. In the final battle against the D-Reaper, Baihumon assisted Azulongmon, Ebonwumon, and Zhuqiaomon into dragging the Cable Reaper back into the Digital World during Operation: Doodlebug, thus saving the Tamers.